what is mesothelioma? mesothelioma caused by asbestos exposure mayprove to be a public health crisis as more people are diagnosed with this rare form ofcancer. mesothelioma, also called malignant mesothelioma,is a rare but deadly form of cancer that typically occurs in the membrane around the lungs, calledthe pleura.
peritoneal mesothelioma, this type of cancer is usually the resultof inhaling asbestos fibers over a long period of time. most people with mesothelioma, were exposedto asbestos at work, such as in a shipyard, an asbestos mine, an automotive plant, orat a construction site.
mesothelioma: what is it? the mesothelium is the generic term used todescribe the lining that covers many organs and body cavities. mesothelial tissue helps to protect organsand minimize trauma during movement. in addition to the pleura, other mesotheliainclude: the peritoneum, which covers the walls ofthe abdominal cavity the pericardium, which encases the heartthe tunica vaginalis testis, which covers the male internal reproductive organsthe tunica serosa uteri, which covers the female internal reproductive organsmesothelioma can affect any of these mesothelial
tissues, though the pleura is by far the mostcommon site. mesothelioma: the asbestos risk factor when asbestos fibers are inhaled into thelungs, they tend to remain there, and with continuous long-term exposure, the fibersbegin to collect at the bottom of the lungs, where they become trapped in the pleura. over time, this can lead to cancer, especiallyif there are other aggravating factors like a genetic predisposition or a history of smoking. "asbestos irritates the lining of the lungand causes inflammation, and then the inflammatory response and the secondary changes in thelungs and pleural space may eventually lead
to a malignant degeneration," explains timothywinton, md, associate professor of surgery and division director of thoracic surgeryat the university of alberta hospital in edmonton, canada. one of the most striking things about mesotheliomais how long it takes for the disease to develop: up to five decades may elapse from initialasbestos exposure to the development of cancer. but when mesothelioma finally develops, itoften becomes very aggressive and can spread beyond the pleura to other mesothelial tissues. the average survival time for malignant mesotheliomaranges between four and 18 months, and about 10 percent of patient live at least five yearsafter being diagnosed.
in rare cases of slow-growing mesothelioma,survival can extend to 20 years. risk factors for mesothelioma mesothelioma is a rare but deadly cancer thataffects the linings of various organs. asbestos exposure is the no. 1 risk factorfor mesothelioma, but other risk factors also have been identified. mesothelioma is a deadly cancer that affectsthe mesothelium. the mesothelium is the membrane, like a net,that covers many organs in the body, such as the lungs and the heart. it has two layers: one covers the organ, theother acts like a sac, letting the organ move,
if necessary. people who develop mesothelioma have usuallybeen exposed to a substance that infiltrated the mesothelium. mesothelioma risk factors: long-term asbestosexposure among the risk factors for mesothelioma, exposureto asbestos dust is by far the most important. about 70 percent to 80 percent of mesotheliomapatients report a history of asbestos exposure at work. and because asbestos was widely used in industry,car manufacturing, and construction until just a few decades ago, millions of u.s. workershad long-term exposure to asbestos and still
are at risk for the disease. leading the list are:asbestos miners shipyard workersmakers of asbestos products and textiles workers in the heating and construction industries mesothelioma risk factors: short-term asbestosexposure many more people with shorter or less intensiveexposure to asbestos face reduced but still real risks. for instance, demolition workers, firefighters,drywall removers, asbestos removal workers, and automobile workers may also be exposedto asbestos fibers.
even family members of asbestos workers maybe exposed to asbestos dust because the workers bring it home on their clothing. one particular group that may be at elevatedrisk are the crews involved in the cleanup of the world trade center in new york cityafter 9/11. asbestos was used in the construction of thenorth tower and it is estimated that hundreds of tons of asbestos were among the debris. the risks posed by asbestos exposure can behard to quantify, but in general risk depends on:the quantity of asbestos the person was exposed tothe length of time the person was exposed
the size, shape, and chemistry of the asbestosfibers personal risk factors, such as smokingthere are two main forms of asbestos, amphibole (straight fibers) and chrysotile (curly fibers). although all asbestos is dangerous, recentstudies suggest that exposure to amphibole asbestos may pose a greater risk of mesotheliomathan chrysotile asbestos because amphibole fibers remain in the lungs longer. mesothelioma: a public health issue mesothelioma is a rare disease � only 2,000to 3,000 new cases are diagnosed each year in the united states.
however, in other countries, the incidenceof mesothelioma continues to increase. "because of the history of the use of asbestosand the known long latency between exposure and development of disease, the incidenceof this type of disease around the world is going to continue to go up through the nexttwo to three decades," dr. winton says. "there are a lot of workers around the worldwho were exposed in an industrial setting and who need to be carefully followed." if you think you have been exposed to asbestos,let your doctor know and make sure you get regular checkups. as with most cancers, early diagnosis is importantto treating this disease.
mesothelioma risk factors: while it is clear that the risks climb withmore intensive exposure over longer periods of time, some people have gotten mesotheliomaafter only brief exposure to asbestos, while others who were intensively exposed do not. "there is a lot of work being done to tryto find links to genetic predisposition to the disease," says timothy winton, md, anassociate professor of surgery, and division director of thoracic surgery, of the universityof alberta in edmonton, canada. "there is also often a co-morbid history ofsmoking or a genetic predisposition to smoking-related problems.
with many cancers � and mesothelioma isone of them � you may need multiple hits from different carcinogens before you developthe disease." mesothelioma risk factors: simian virus 40(sv40) in the 1950s some polio vaccines were contaminatedwith sv40, which has been shown to cause mesothelioma in laboratory animals. in humans, an association between sv40 andmesothelioma has been suggested because sv40 has been found in human mesothelioma tumors,but no clear connection has been established. mesothelioma risk factors: thorium dioxideand x-ray imaging some studies have linked the use of the x-rayradioactive contrast medium thorium dioxide
(thorotrast) to an increased incidence ofcancer, including mesothelioma. one study found that a group exposed to thoriumdioxide had a cumulative incidence of peritoneal mesothelioma (the peritoneum lines the stomachcavity) as much as 0.6 percent higher than asbestos-exposed workers. thorium dioxide has not been used in x-rayimaging for many years. mesothelioma risk factors: zeoliteszeolites are minerals found naturally in volcanic rock and ash that contain hydrated aluminumand silicon. in synthetic forms, zeolites are used in detergents,for water and air purifications, and in other uses.
exposure to airborne zeolite dust has beenassociated with high incidence of mesothelioma in turkey. in one turkish village, a form of zeoliteused to whitewash houses caused pleural mesothelioma incidence to soar to 440.9 per 100,000 forwomen and 298.1 per 100,000 for men. links are very importantwhat are symptoms of mesothelioma ? https://www.youtube.com/watch?v=7kvxbounkhu&index=1&list=pllnrv2p827em0zad7ittoa6mf7l26qctu&t=406s mesothelioma prognosishttps://www.mesothelioma.com/mesothelioma/prognosis/
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